James Henry, PhD
Michael G. DeGroote Institute for Pain Research and Care,
Health Sciences Centre
James Henry is a neurophysiologist who has worked throughout his career to understand the underlying mechanisms of acute and chronic pain. In January 2005, he joined McMaster as the inaugural scientific director of the Michael G. DeGroote Institute for Pain Research and Care, and as a professor in the Departments of Psychiatry and Behavioural Neurosciences, and Anesthesia. He also holds a newly endowed chair in central pain.
Henry founded the Canadian Consortium on Pain Mechanisms, Diagnosis and Management, which is comprised of 40 top pain researchers in a multidisciplinary, all-Canadian think-tank to promote pain research, improve pain management and disseminate information on pain to patients, practitioners and policymakers. He is also president and chairman of the board of the Canadian Pain Foundation, and is a past-president of the Canadian Pain Society.
His current research is funded by the CIHR and the Canadian Arthritis Network (CAN) for a New Emerging Team, providing $1.5 million over a five-year period. This project is “Molecular mechanisms of the pain and fatigue of osteoarthritis: interplay between nerve and joint.” Henry also holds a medical school grant from Merck for a study on the pain of diabetic neuropathy.
- Henry JL. Future basic science directions into mechanisms of neuropathic pain. Journal of Orofacial Pain. 2004; 18(4):306-10.
- Henry JL. Molecular events of chronic pain: From neuron to whole animal in an animal model of osteoarthritis. Novartis Foundation symposium. 2004; 260:139-45; discussion 145-53, 277-9. Review.
- Pitcher GM, Henry JL. Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain. Experimental Neurology. 2004; 186(2):173-97.
- Pitcher GM, Henry JL. Second phase of formalin-induced excitation of spinal dorsal horn neurons in spinalized rats is reversed by sciatic nerve block. The European Journal of Neuroscience. 2002; 15(9):1509-15.
- Pitcher GM, Henry JL. Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation. Neuroscience Letters. 2001; 305(1):45-8.